刘芷绚生长在马来西亚阳光普照的热带海岛Langkawi。身高1.72m的她人如其出生的地方一样，全身充满着一股健康的阳光气息。2001年毕 业于马来西亚Saito Academy后，由于身高占了优势，刘芷绚加入了模特儿行列，开始了在天桥上走猫步。除此之外，她也尝试客串过当地的几部电视制作。
Jesseca Liu was born in Langkawi, Malaysia. She began modeling after graduating from Saito Academy in 2001. Languages often spoken by Liu are Cantonese, Mandarin, English and Bahasa Melayu. First known as Jesseca Lao Chew Yen, she finished second for a Malaysian beauty contest in 2001. Jesseca began acting in Malaysia with a few Chinese drama productions.
In 2004, Jesseca was spotted by a producer in MediaCorp who offered her the attractive role of He Yi Xuan in the sports drama, The Champion, starring opposite Qi Yu Wu and Taiwanese Toro and Yan Xing Shu. She begin a career as a full time actress in Singapore.
She had a role in Portrait of Home, where she played a Vietnamese bride, Ruan Mianmian. She was nominated for Best Supporting Actress and Most Popular Newcomer Award categories during Star Awards 2005 with her role as Ruan Mianmian in Portrait of Home. She earned the Most Popular Newcomer Award that year.
Her first lead role was as Ding Yirou in Rhapsody In Blue in 2006. She was given opportunities to play the lead roles thereafter. She filmed a movie by Raintree Picture (Singapore) back in year 2007 and it was scheduled to be screened in the second quarter of 2008. However, the screening of the movie was put to a halt due to copyright problems.
Jesseca released a book diary, ‘Jesseca’s Diary’ (Chinese : 绚日记) in December 2007.
Jesseca’s contract with Mediacorp ended in May 2010, and she had just signed a contract with Singapore’s HIM Music Label in the year 2010. Her first production under her new company was Channel U’s 2010 feature film, Lost and Found 《小孩·狗》with Taiwan’s popular child star Xiao Xiao Bin and Taiwanese idol James Wen Sheng Hao. The film garnered the highest viewership amongst the other two feature films aired, starring Mediacorp actresses Joanne Peh and Felicia Chin in each.
She is involved in Mediacorp Channel U’s 2011 blockbuster drama, Secrets For Sale 《拍。卖》as the main lead actress alongside Mediacorp actors Christopher Lee and Thomas Ong who are the first and second lead actors respectively. The drama is scheduled to be aired on the 14th of March 2011.